Comments on: What is GABA Deficiency?

By: Walter Futch, DDS

Walter Futch, DDS — Fri, 26 Jul 2019 21:02:48 +0000

Glutamate transformation to GABA requires GAD65 enzyme. People with GAD65 antibodies cannot make this conversion and have Stiff Person Syndrome. I have it and iT takes all the fun out of life. All the symptoms above apply to SPS plus excruciating muscle spasms, frequent falls, as well as reaction to loud noises, intolerance to exercise, pain on walking stiff fingers, etc..I had to retire due to finger spasms as well as back and foot spasms.

By: Steven B

Steven B — Tue, 04 Jun 2019 18:46:04 +0000

Thank you for this! I really like how concise this explains things with citations. I find myself trying to describe some of these topics to people but this does it so much better. I have narcolepsy and am currently on Xyrem now, which is one of many things that helps my absurdly low levels of GABA. I would love to see some research on what causes a low level.

By: Jane

Jane — Wed, 01 May 2019 14:58:52 +0000

I was on venlafaxine..discovered I couldn’t tolerate it. I had all 59 thousand sideeffects. I went off the medication against my Dr. Advise…weaned myself off. Got. Gaba to take and after a while started 350 milligrams. I have seen a lot of good things about gaba..just now taking it. How long does it take to work?..it is something we already have receptors for so I am hopeful.

By: CinnaGoo

CinnaGoo — Thu, 21 Mar 2019 03:46:19 +0000

Acupuncture is non-scientific nonsense. Sticking needles into your body does not help or cure anything. This article lost all credibility as soon as I saw acupuncture as a fix for low GABA levels.

By: Reka Szebenyi

Reka Szebenyi — Wed, 27 Feb 2019 07:12:16 +0000

Gaba means everything to me. 10 years in and out of deeeeep depressions.. body shivering a lot..getting spasms.. feeling ridid..stiff… Anxious. Ten years if hell.. after gaba i am again my nirmal self.And enjoy being alive. I love Gaba.. yes it does crosdes the bbb

By: Nancy Orban

Nancy Orban — Thu, 06 Dec 2018 15:08:59 +0000

You may want to peruse: http://www.benzoinfo.com; http://www.W-BAD.org; http://www.PointofReturn.com; http://www.breggin.com; http://www.everywomanover29.com. Also keywords: GABA Glutamate balance (Mullan, M.D., holistichelp.net…

By: Dee Anders

Dee Anders — Mon, 17 Sep 2018 19:20:24 +0000

Fred, I think what you might find success in changing your focus from increasing GABA to decreasing glutamate. You appear to have too much stress in your system, which will lower GABA no matter what you do. Glutamate has taken over, which produces a lot of anxiety and stress. You appear to be doing a lot of stress relieving behaviors. When you get your glutamate at much lower levels, your natural GABA should increase. So, it is about creating a lifestyle of much lower stress. Meditation has been shown to work just as well, if not better, than medications because it fixes the stress response in the brain. It is easy to meditate with helpful meditation CD’s that help train your brainwaves to a calmer pattern. I like the ones sold by Centerpointe.com. I have no affiliation with them. Blessings in your journey!

By: Fred

Fred — Tue, 11 Sep 2018 09:15:39 +0000

My symptoms of (what i think is) Gaba deficiency, which almost always are preceded by my body temperature decreasing significantly even indoors (or at least extremities feeling cold and then muscles starting to tense up) are headache, muscle tension, blood vessel tension (they contract because they have muscles too, and blood flow decreases, a negative spiral) and one feels cold, and it hurts in the tensed body and muscles, anxiety, mild paranoia/blaming a little too much, and then after some hours one feel one had enough and starts getting angry, sleep problem, racing thoughts, emotional roller coaster from angry to sad but never feeling satisfied, calm and relaxed which is what one yearns for, so… i start overeating and getting fatter and fatter, because i feel calmer after candy, chocolate bars, protein bars and all that, but isn’t food increasing serotonin, so i wonder if i have gaba or serotonin deficiency? I take a hot shower to relax my muscles, afterwards i feel calm, when i feel cold then the muscle tension starts again and i feel the gaba-deficiency mood coming back. Magnesium glycinate helps me, magnesiumhydroxid makes pain in joints, and magnesium citrate is muscle relaxing for 30 min but afterwards my citric acid allergy kicks in and i get skin rash. Alcohol helps too, it makes me warm and relaxed and sometimes energetic (i think i have often low dopamine as well), but afterwards i feel even more tensed, cold and tired so i don’t use it for this gaba problem. What i am worried about is that using GABA boosting herbs and stuff can desensitize my GABA receptors because of increased tolerance and then one will feel even more tensed and angry. I wish there are some really good stuff for this problem without negative side effects.

By: B.M

B.M — Thu, 09 Aug 2018 19:59:55 +0000

Dr.A, of course there are cases in which sever eanxiety can’t be controlled with passiflora and lettuce, have you read the indications that is indicated for mild symptoms? The problem with benzo’s is that they can lead to addiction in case your symptoms or discomfort continues.

By: N.W.

N.W. — Thu, 12 Apr 2018 21:06:58 +0000

Can we agree that one size does not fit all and that a treatment that works in some cases will not work in all of them ? Myself and four of my adult children have taken GABA 1000mg daily for years. It enables us to be free of the cognitive paralysis which besets us when we go for a week without GABA. My understanding is that GABA is effective is specific phenotypes. In our case we have injuries ranging from severe TBI to a series of mild bumps to the head over several years. It helps to calm the “what ifs” often associated with cumulative head trauma. I have suggested this to many patients over the past 7 years with 85% voicing improvement within one month of daily dosing. Yes, I kept records and did the math: the total number of patients who reported back was 115. This is simply my experience. I will continue to recommend GABA for those who have a mild paranoia (blaming, anxiety), difficulty completing simple actions because they are concerned that “somehow it might turn out badly”, and constant thoughts of things that need to be done even though those tasks may be slated for a week or more away.